TARDIGRADES : SCIENCE & TECHNOLOGY

NEWS: Researchers Uncover Genetic Mechanisms in New Tardigrade Species That Enable Radiation Resistance, Paving the Way for Medical and Space Exploration Advances

 

WHAT’S IN THE NEWS?

Researchers recently identified a new species of tardigrade, Hypsibius henanensis, capable of withstanding extreme radiation levels.This microscopic organism, found in moss samples from Funiu Mountain in China, activates thousands of genes under radiation exposure, which protect and repair its DNA.

General Facts:

·         Also called water bears or moss piglets; microscopic, eight-legged invertebrates.

·         Belong to the phylum Tardigrada; around 1,300 species found worldwide.

Habitat:

·         Prefer freshwater mosses and lichens but can survive in various environments, including deep sea and sand dunes.

·         Known as extremophiles for their ability to endure extreme conditions: intense heat, cold, radiation, and even outer space.

·         In adverse conditions, they enter a "tun" state of suspended animation, surviving for years or even decades.

Physical Features:

·         Tiny (around 1 mm), with four pairs of clawed legs and no bones, supported by a hydrostatic skeleton.

·         Tough cuticle that is shed to grow; specialized mouthparts for sucking nutrients from plants and microorganisms.

Study on Radiation Resistance:

·         Genome sequencing revealed 14,701 genes in the species Hypsibius henanensis, with 30% unique to tardigrades.

·         Exposed to high doses of gamma rays to study survival mechanisms.

Key Mechanisms for Radiation Resistance:

1.      DNA Repair Protein (TRID1): Repairs DNA double-strand breaks.

2.      Mitochondrial Synthesis Proteins: Assist in DNA repair during radiation.

3.      Antioxidant Pigments (Betalains): Neutralize reactive chemicals from radiation.

Potential Applications:

·         Findings may aid space travel, nuclear cleanup, and cancer treatment.

·         Tested on human cells, betalains improved cell survival under radiation, indicating future potential for human radiation protection.