GARBH-INI - SCIENCE AND TECHNOLOGY

News: Indian scientists find genetic markers linked to premature births

 

What's in the news?

       For the first time in South Asia, Indian scientists working in the Garbh-Ini programme, an interdisciplinary group for advanced research on birth outcomes, have identified 19 single nucleotide polymorphisms (SNPs), or genetic markers, that have been found to be associated with preterm or premature birth.

 

Key takeaways:

       The study, published in the Lancet Regional Health-South East Asia journal, reported that five of these SNPs have been found to “confer increased risk of early preterm birth (birth before 33 weeks)’’ and can predict premature births.

 

Garbhi-Ini:

       It is an interdisciplinary research program in India that focuses on the advanced research of birth outcomes.

       Garbh-Ini is an initiative under the Department of Biotechnology as a collaborative interdisciplinary programme, led by DBT-Translational Health Science and Technology Institute (THSTI), NCR Biotech cluster, Faridabad, in collaboration with DBT-NIBMG, Kalyani, DBT-Regional Centre for Biotechnology (RCB), Gurugram Civil Hospital and other organisations.

       The program aims to use advanced technology to improve maternal and child health outcomes and address the high incidence of preterm births in India.

 

Genetic Markers:

       Genetic markers are specific sequences of DNA that can be used to identify an individual or a particular trait.

       Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation that occurs in the DNA sequence.

       SNPs occur when a single nucleotide (A, C, T, or G) in the DNA sequence is altered.

       These changes can occur in any region of the genome and can be used as genetic markers to identify specific traits or disease susceptibility.