CRITICAL PRIORITY PATHOGENS - SCI & TECH

News: WHO updates Bacterial Pathogens Priority List as critical priority pathogens continue to present major global threat

 

What's in the news?

       The latest Bacterial Pathogens Priority List (BPPL) updated by the World Health Organization (WHO) notes that critical priority pathogens pose major global threats because of their high burden and their ability to resist treatment and spread resistance to other bacteria.

 

Critical Priority Pathogens:

       They are bacteria that pose significant global health threats because they can resist current treatments and spread their resistance to other bacteria.

 

World Health Organization’s Updated List:

       The WHO has updated its Bacterial Pathogens Priority List (BPPL). 

       It includes 15 families of antibiotic-resistant bacteria.

 

Classification of the BPPL:

       Critical Priority Groups

       High Priority Groups

       Medium Priority Groups

 

High Burden in Specific Regions:

       The list highlights that certain high-priority pathogens like Salmonella and Shigella carry a particularly high burden in low and middle-income countries.

       These pathogens pose major challenges in healthcare settings.

 

 

Resistance to Antibiotics:

       These pathogens include gram-negative bacteria that are resistant to last-resort antibiotics and Mycobacterium tuberculosis that is resistant to Rifampicin which is a key antibiotic.

 

Challenges Associated with Critical Priority Pathogens:

       Pathogens like antibiotic-resistant Neisseria gonorrhoeae and Enterococcus faecium are known for causing persistent infections and showing resistance to multiple antibiotics.

       This necessitates targeted research and public health interventions.

 

 Go back to basics:

Antimicrobial Resistance (AMR):

       AMR occurs when bacteria, viruses, fungi, and parasites no longer respond to medicines.

       This makes infections harder to treat and increases the risk of disease spread, severe illness, and death.

       The misuse and overuse of antimicrobials are significant drivers of AMR.