CHIMAERAS - ENVIRONMENT

News: The chimaeras of nature and their promise to grow human organs | Explained

 

What's in the news?

       At present, more than 3 lakh people are waiting for an organ transplant in India alone; the global number is far higher, with no respite in sight.

       There is an alarming disparity in the number of organ donors and the number of recipients – and animals have played an important part in filling this gap.

 

Chimaeras:

       Chimaeras are organisms that are made up of the cells of two distinct species.

       For instance, if this hybrid embryo is placed in the womb of a monkey, it could possibly grow into a new kind of animal.

 

Research:

       Scientists have injected human stem cells (cells that have the ability to develop into many different body tissues) into the macaque monkey embryos. This integration created a chimeric tool.

 

Purpose of Chimera Research: 

Researchers believe that the ability to grow cells of two different species together helps scientists in research and Medicine such as:

       Advancing current understanding about early human development.

       Understanding disease onset and progression.

       Drug evaluation.

       Address the critical need for organ transplantation.

 

Concerns Regarding Chimera Research:

1. Moral Dilemma: 

       Humans are widely thought to have a higher moral status than other animals. But human-animal chimeras blur this line. These Chimeras are not fully human nor fully non-human.

2. Survival Issues: 

       Some rare hybrid animals exist naturally probably as a result of unintentional cross-breeding between animals of different species.

       However, generally different species don’t cross-breed. But if they do, their offspring don’t survive for long and are prone to infertility.

3. Issue of Infertility:

       Mules are an example of a hybrid animal that is the result of mating between a female horse and a male donkey.

       Mules can live a long healthy life. But they are infertile which means that they cannot have offspring of their own.

4. Injustice Against Animals for Human Needs: 

       Chimera research has the potential to worsen injustice against animals as it is being done to meet human needs.